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A Comprehensive
Policy and Plan
to Eliminate the
Arthrogryposis
Multiplex (AM)
Gene in the AGA
Herdbook
Contents:
Follow links to
sections below
Section 1:
Official
Designations
Section 2: A.I.
Sires
Section 3: Donor
Females
Section 4:
Required Testing
and Registration
Requirements
Section 5:
Testing
Laboratories
Section 6:
AM-Free
Designations
Section 7:
Breeder
Awareness
AGA's Position
Statement
(Click
here to view
document as a
PDF)
Gelbvieh Board
Approves
Aggressive
Policy to
Eliminate AM
Gene Press
Release 2/16/09
Additional AM
Information
Section 1:
Official
Designations on
Registration
Certificates and
other Animal
Records
The AGA will
initiate a
genotype
designation
scheme for DNA
tested cattle
and non-tested
cattle at risk
of being a
carrier. These
designations
will appear as
part of the
animal’s record
in all
documentation
available to AGA
members and
other interested
parties.
Actual
Genotype
designations:
-
AM-Free
= Free or
clean by DNA
test
-
AM-Carrier
= an animal
that is
determined
to be a
carrier by
DNA test or
is a
confirmed
parent of an
afflicted
progeny
-
AM-Afflicted
=
designation
for an
animal,
entered in
the AGA
Herdbook for
parentage
and official
record
reasons,
reported to
the AGA,
confirmed to
be a “Curly
Calf” and
parent
verified.
Parents
would
receive the
AM-Carrier
designation.
Inferred
Genotype
designations:
-
AM-50
- designated
on cattle
that have
one or more
AM-Carrier
parents or
more than
one
AM-Carrier
grandparent.
-
AM-25
– designated
on cattle
having one
AM-Carrier
grandparent.
Inferred
designations
would be
replaced with an
actual genotype
designation when
an animal is DNA
tested.
Section 2: A.I.
Sires
All sires for
which A.I.
Permit
applications are
submitted to the
AGA starting
January 1, 2009
must be tested
“AM-Free” in
addition to the
longstanding
parent
verification
requirement. The
AM testing and
parent
verification
must be done
from a single
sample submitted
to AGA’s
official parent
verification
lab.
(Including
Gelbvieh bulls
is a risk
assessment and
may not be
required long
term.)
A.I. Bulls,
which possess an
inferred
genotype (AM-50
or AM-25)
indicating risk
(their pedigree
traces to a
known Angus
carrier) and
which have A.I.
permits issued
before January
1, 2009 will be
AM tested at the
owner’s expense.
The AGA will
notify owner(s)
of the
requirement to
test (primarily
Balancer bulls).
AM testing in
this case must
also be done at
the AGA’s
official parent
verification
lab.
If the owner(s)
fail to test an
A.I. bull with
an inferred risk
genotype, all
progeny born on
or after January
1, 2010 will be
subject to the
testing
requirements and
registration
restrictions as
outlined below
as if the sire
is an
AM-Carrier. This
avenue could be
used in the case
of a deceased
bull with rare
and valuable
semen being the
only means of
testing.
The AGA will
test the 30 most
popular Gelbvieh
sires as a risk
assessment.
Section 3: Donor
Females
All Angus,
Balancer and
Angus derivative
females that do
not have the
required donor
female DNA
Profile on file
with AGA’s
official
laboratory as of
January 1, 2009
will be required
to be DNA tested
for the AM gene
in addition to
their profile.
Donor female
profile and AM
testing must be
done at AGA’s
official parent
verification
lab.
ET progeny will
fall under the
Required Testing
and Registration
Requirements
outlined below.
4. Required
Testing and
Registration
Requirements
The AGA reserves
the right to
test any animal
as provided in
the Bylaws of
the
organization.
All females with
an inferred
genotype of
AM-50, which are
retained for
breeding, are
required to be
tested. This
testing must be
completed at
Igenity, AGA’s
official parent
verification lab
and samples are
subject to
parent
verification at
AGA’s request
and expense.
The AGA will
underwrite
$10.00 of the
testing expense
as a rebate for
the first 500
females with an
AM-50 inferred
genotype.
Breeders must
apply for the
rebate after the
results are
reported to the
AGA. Application
deadline is
December 31,
2009 or when 500
tests have been
conducted,
whichever comes
first.
Any animal
presented for
registration
that has an
undocumented
Angus parent or
an Angus
derivative
parent, i.e. an
“Angus
Foundation Cow”,
is subject to
the same testing
requirements and
registration
restrictions as
outlined below
as if the
undocumented
Angus parent is
an AM-Carrier.
All cattle born
on or after
January 1, 2010
with an
AM-Carrier or an
AM-50 sire
and/or an
AM-Carrier dam
will be required
to be DNA tested
and the test
result will be
reflected as the
genotype
designation in
their record and
on all
documentation.
All cattle born
on or after
January 1, 2011
with one or more
AM-Carrier,
AM-50 or AM-25
parents will be
required to be
DNA tested and
the test result
will be
reflected as the
genotype
designation in
their record and
on all
documentation.
All cattle born
on or after
January 1, 2012
with one or more
AM-Carrier,
AM-50 or AM-25
parents will be
required to be
DNA tested and
test AM-Free to
be eligible for
registration.
The records of
AM-Carrier
designated
cattle born on
or after January
1, 2012 will be
accepted as
‘computes’ for
genetic
evaluation
purposes, their
performance data
within a
contemporary
group will
contribute to
their parent’s
genetic
evaluation but
no EPD values
will be
available on
AM-Carrier
animals born on
or after January
1, 2012.
Section 5:
Testing
Laboratories
The AGA will
maintain a list
of laboratories
that can test
cattle for the
AM gene and will
accept results
from those labs.
Animals must be
identified by
registration
number at the
time the sample
is submitted for
testing.
Breeders should
be aware that
AGA’s official
lab for
parentage,
Igenity is
providing AM
testing services
and if disputes
occur that would
require DNA
parent
verification of
a sample it may
be more cost
effective for
breeders to have
the AM testing
done at Igenity.
Section 6:
AM-Free
Designations
Guidelines are
being developed
for breeders
wishing to use
an AM-Free claim
in promotion of
their herd, sale
offering or
individual
cattle.
Section
7:Breeder
Awareness
The AGA will use
its best efforts
to alert members
of potential
carriers in
their herd and
will continue
educational
programs to
assist breeders
in their efforts
to eliminate the
AM gene.
However, the AGA
assumes no
liability for
overlooking
potential
carriers or
inadvertently
naming potential
carriers that
may in fact not
be carriers in
member herds.
Staff will
assist breeders
in developing
cost effective
plans to test
cattle, i.e.
testing an old
Angus suspect
cow and finding
her to be clean
could eliminate
the necessity of
testing progeny
and grand
progeny.
AGA’s Position
Statement
The American
Gelbvieh
Association has
historically
enjoyed a very
high level of
integrity among
its member
breeders and an
excellent
reputation in
the livestock
industry. That
level of
integrity, the
power of
available
technology, and
the common
spirit for breed
improvement will
be instrumental
in eliminating
the
Arthrogryposis
Multiplex (AM)
gene.
While the
problem
originated
outside our
breed, the AM
gene impacts
several major
breeds with
upgrading
programs and
hybrid and
composite
programs that
have
incorporated
Angus genetics.
Seedstock
breeders of all
of the impacted
breeds must
recognize that
with today’s DNA
technology, the
risk of
knowingly
selling or
misrepresenting
carrier cattle
is much greater
than any
short-term
financial gain.
It is extremely
shortsighted to
think that the
AM gene is not
already present
in commercial
cowherds and
that end users
of carrier
genetics cannot
be financially
impacted.
Our goal is to
eliminate the AM
gene from the
population in
the American
Gelbvieh
Association’s
Herdbook. We
will monitor the
action of
breeders and
progress toward
this objective
and reserve the
right to adjust
these policies
to achieve that
goal.
The quality of
the people
involved in
breeding
Gelbvieh and
Balancer cattle
and the great
genetics the
Gelbvieh breed
possess are our
greatest assets.
The AGA Board of
Directors
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